Proposal for a Study Protocol on the Use of Antioxidants as Adjuvants in Cancer Therapy

Main Article Content

Giovanni Puccio
Massimo Coppolino

Abstract

A protocol is proposed for studying the effects of oxidant substances, such as GSH, NAC, and vitamin C, in combating tumors as an adjuvant to chemotherapy. These same substances are combined, at different times and in different cases, with molecules such as phosphatidylethanolamine and ivermectin, and the use of alternative techniques such as oxigen-ozone Therapy o byorisonance. These molecules are currently being studied for their efficacy at various research centers. Given their biochemical compatibility, the author has decided to combine these with antioxidants and their proven activity as catalysts of antitumor processes.
The protocol draws not only on the abundant literature confirming that the use of antioxidants, with precise timing of administration, can facilitate recovery from cancer when combined with chemotherapy, but also that they can drastically reduce both the duration of treatment and hospitalization and death rates. Furthermore, the author, who has analyzed numerous cases, has noted that it leads to an almost complete reduction in side effects, lowering chemotherapy-induced toxicosis. Relapses also appear to be reduced compared to the average.
For this reason, we will first analyze the individual substances and how they interact with each other, bridging different cellular life cycles that only apparently appear unrelated but which, as has been demonstrated, are the basis for the development of many forms of cancer.

Article Details

Puccio, G., & Coppolino, M. (2026). Proposal for a Study Protocol on the Use of Antioxidants as Adjuvants in Cancer Therapy. Archives of Case Reports, 43–57. https://doi.org/10.29328/journal.acr.1001188
Research Articles

Copyright (c) 2026 Coppolino M.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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