Other Applications of Amniotic Membranes: Case Series
Main Article Content
Abstract
The amniotic membrane, used for over a century, is a widely recognized therapeutic tool in regenerative medicine and reconstructive surgery. Its primary indication is in the treatment of deep partial-thickness burns, where it facilitates epithelialization by providing an optimal environment for tissue regeneration. However, its versatility allows its use in various clinical scenarios, particularly in wounds or trauma where immediate closure is not possible, either due to the patient’s condition or the characteristics of the wound itself. Its most notable benefits include the prevention of necrosis due to desiccation, minimizing the loss of essential proteins, fluids, and electrolytes, reducing the risk of infection by acting as a physical barrier and alleviating pain by covering and stabilizing the wound.
Additionally, its ability to act as a temporary biological cover offers a valuable solution in complex cases, improving both the prognosis and the patient’s management.
A case series is presented demonstrating various applications of the amniotic membrane.
Article Details
Copyright (c) 2024 Guerrero L.

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Trelford JD, Trelford-Sauder M. The amnion in surgery, past and present. Am J Obstet Gynecol. 1979;134(7):833-845. Available from: https://doi.org/10.1016/0002-9378(79)90957-8
Robson MC, Krizek TJ. The effect of human amniotic membranes on the bacterial population of infected rat burns. Ann Surg. 1973;177:144-149. Available from: https://doi.org/10.1097/00000658-197302000-00003
Robson MC, Krizek TJ. Amniotic membranes as a temporary wound dressing. Surg Gynecol Obstet. 1973;136:904-906. Available from: https://pubmed.ncbi.nlm.nih.gov/4703471/
Fairbairn NG, Randolph MA, Redmond RW. The clinical applications of human amnion in plastic surgery. J Plast Reconstr Aesthet Surg. 2014;67(5):662-675. Available from: https://doi.org/10.1016/j.bjps.2014.01.031
Branski LK, Herndon DN, Celis MM, Norbury WB, Masters OE, Jeschke MG. Amnion in the treatment of pediatric partial-thickness facial burns. Burns. 2008;34(3):393-399. Available from: https://doi.org/10.1016/j.burns.2007.06.007
Vloemans van der Wal H, Liebregts J, Middelkoop E. Optimal treatment of partial thickness burns in children: A systematic review. Burns. 2014;40(2):177-190. Available from: https://doi.org/10.1016/j.burns.2013.09.016