An unusual clonal chromosome abnormality der(17)t(11;17)(q24;p13)inv(11)(q13;q23) in a patient with chronic lymphocytic leukemia

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Submitted: September 21 2021
Published: Nov 10, 2021
DOI: 10.29328/journal.acr.1001053
Keywords:
Der(17);, CLL;, Pseudocentric chromosome, FISH, Oncology
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Valentina Monti*
Department of Pathology, National Cancer Institute of Milan, Italy
Fabio Serpenti
Department of Clinical Oncology and Hematology, National Cancer Institute of Milan, Italy
Lucia Farina
Department of Clinical Oncology and Hematology, National Cancer Institute of Milan, Italy
Maria Luisa Moiraghi
Department of Pathology, National Cancer Institute of Milan, Italy
Maria Adele Testi
Department of Pathology, National Cancer Institute of Milan, Italy
Giancarlo Pruner
Department of Pathology, National Cancer Institute of Milan, Italy

Article Details

Monti, V., Serpenti, F., Farina, L., Moiraghi, M. L., Testi, M. A., & Pruner, G. (2021). An unusual clonal chromosome abnormality der(17)t(11;17)(q24;p13)inv(11)(q13;q23) in a patient with chronic lymphocytic leukemia. Archives of Case Reports, 5(2), 028–031. https://doi.org/10.29328/journal.acr.1001053
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Copyright (c) 2021 Monti V, et al.

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Buccheri V, Barreto WG, Fogliatto LM, Capra M, Marchiani M. Prognostic and therapeutic stratification in CLL: focus on 17p deletion and p53 mutation. Ann Hematol. 2018; 97: 2269-2278. PubMed: https://pubmed.ncbi.nlm.nih.gov/30315344/

Stankovic T, Skowronska A. The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia. Leuk Lymphoma. 2014; 55: 1227-1239. PubMed: https://pubmed.ncbi.nlm.nih.gov/23906020/

Stilgenbauer S, Lichter P, Dohner H. Genetic features of B cell chronic Lympocytic leukemia. Rev Clin Exp Hematol. 2000; 4: 48-72. PubMed: https://pubmed.ncbi.nlm.nih.gov/11486330/

Oliveira-Junior RJ, Filho LRG, Bastos LM, Alves DD, Vaz dos Santis S. Contribution of cytogenetics to cancer research. 2014; 30: 245-259.

Barra V, Fachinetti D. The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA. Nat Commun. 2018; 9: 4340. PubMed: https://pubmed.ncbi.nlm.nih.gov/30337534/

Khanna KK, Stephen PJ. DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet. 2001; 27: 247-254. PubMed: https://pubmed.ncbi.nlm.nih.gov/11242102/

Schaffner C, Idler I, Stilgenbauer S, Dohner H. Lichter P. Mantle cell lymphoma is characterized by inactivation of the ATM gene. Proc Natl Acad Sci USA. 2000; 97: 2773-2778. PubMed: https://pubmed.ncbi.nlm.nih.gov/10706620/

Shaffer LG, McGowan-Jordan J, Schmid M. An International System for Human Cytogenetic Nomenclature (ISCN). Basel. 2013.