Abstract

Case Report

Brooke-Spiegler Syndrome: A rare cause of skin appendageal tumor

N Suganthan*, S Pirasath and DD Dikowita

Published: 01 November, 2018 | Volume 2 - Issue 1 | Pages: 016-018

A 51-year-old women presented with asymptomatic multiple polypoidal nodules over scalp with simultaneous papularnodular skin eruptions involving nose, nasolabial folds and forehead for 40 years duration. Her daughter also noted to be having multiple papularnodular skin eruptions involving nose, nasolabial folds and forehead which raised curiosity of possible familial condition. The punch biopsy of polypoidal nodule indicating histological evidence of spiradenoma was favour in diagnosis of Brook Spienger Syndrome. We report this case as this is a rare clinical entity.

Read Full Article HTML DOI: 10.29328/journal.acr.1001009 Cite this Article Read Full Article PDF

Keywords:

Brooke- spiegler syndrome; Skin adnexal tumors

References

  1. Ekmekci TR, Koslu A, Sakiz D. Congenital blaschkoid eccrine spiradenoma on the face. Eur J Dermatol. 2005; 15: 73-74. Ref.: https://goo.gl/Kptefn
  2. de Andrés Gómez A, Navarro Moratalla C, Villalba Ferrer F, Sabater Marco V, García-Vilanova A, et al. Malignant eccrine breast spiradenomas. A case report and literature review. Int J Surg Case Rep. 2015; 15: 81-84. Ref.: https://goo.gl/QzzVqM
  3. Bumgardner AC, Hsu S, Nunez-Gussman JK, Schwartz MR. Trichoepitheliomas and eccrine spiradenomas with spiradenoma/cylindroma overlap. Int J Dermatol. 2005; 44: 415-417. Ref.: https://goo.gl/tqp7T3
  4. Bowen S, Gill M, Lee DA, Fisher G, Geronemus RG, Vazquez ME, et al. Mutations in the CYLD gene in Brooke-Spiegler syndrome, familial cylindromatosis, and multiple familial trichoepithelioma: lack of genotype-phenotype correlation. J Invest Dermatol. 2005; 124: 919-920. Ref.: https://goo.gl/MWUAy8

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